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Here is information from CCIT about installing EndNote: https://ccit.clemson.edu/support/faculty-staff/software/individual-licenses/?id=783&l=0
If you have trouble installing, unzip/extract both files to a folder first, before opening the installer. If you are asked for a product key, it's because you didn't extract both the EN21Inst.msi AND the License.dat files first. Do this, and try the installation again.
If you have questions, email ithelp@clemson.edu.
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